abstract：:Components of the communication system between infant and adult rodents based on ultrasonic vocalizations (USVs) of infants are analyzed. USVs are most often emitted from a pup lost outside the nest in response to changes of: (i) body temperature, (ii) contact with adults/littermates, (iii) handling, and (iv) smell. T...

journal_title：Behavior genetics

authors： Ehret G

更新日期：2005-01-01 00:00:00

abstract：:Genetic strains of mice represent an important resource for research on the biological determinants of complex diseases and behavioral phenotypes. To date, the approaches used have had little success in identifying causal genes. We have evaluated brain gene expression in C57BL/6J (B6) and DBA/2J (D2) inbred mouse stra...

journal_title：Behavior genetics

authors： Treadwell JA,Pagniello KB,Singh SM

更新日期：2004-07-01 00:00:00

abstract：:Heterozygous staggerer mice (Rora(+)/Rora(sg)) and control mice (Rora(+)/Rora(+)) of the same C57BL/6J strain background were tested in a spontaneous alternation task at 3 to 24 months old. The results demonstrated a decrement in long-term working memory as early as 6 months in Rora(+)/Rora(+) mice and at 3 months in ...

journal_title：Behavior genetics

authors： Caston J,Chianale C,Mariani J

更新日期：2004-05-01 00:00:00

abstract：:Variance components analysis provides an efficient method for performing linkage analysis for quantitative traits. However, power and type 1 error of variance components-based likelihood ratio testing may be affected when phenotypic data are nonnormally distributed (especially with high values of kurtosis) and there i...

journal_title：Behavior genetics

authors： Shete S,Beasley TM,Etzel CJ,Fernández JR,Chen J,Allison DB,Amos CI

更新日期：2004-03-01 00:00:00

abstract：:Anxiety disorders are phenotypically complex and may involve multiple genetic influences on many neurotransmitter systems. Rodent tests used to investigate genetic influences on anxiety-like phenotypes have face and predictive validity as models for anxiety in humans. If multiple genes contribute additively to a trait...

journal_title：Behavior genetics

authors： Conti LH,Jirout M,Breen L,Vanella JJ,Schork NJ,Printz MP

更新日期：2004-01-01 00:00:00

abstract：:Based on the reviewed literature and the data presented in this paper, conclusions can be drawn with respect to the validity of the WAG/Rij strain of rats as a model for absence epilepsy in humans. The view that the WAG/Rij model has "face validity" is supported by the simultaneous presence of clinical and electroence...

journal_title：Behavior genetics

authors： Coenen AM,Van Luijtelaar EL

更新日期：2003-11-01 00:00:00

abstract：:Previous studies suggest that brain opioid activity decreases aggression in animal models. The main objective of the current study was to examine the possible genetic relationship between intermale aggression and brain levels of enkephalins, endorphins, and dynorphins in 11 inbred strains of mice. Pursuit, rattling, a...

journal_title：Behavior genetics

authors： Tordjman S,Carlier M,Cohen D,Cesselin F,Bourgoin S,Colas-Linhart N,Petiet A,Perez-Diaz F,Hamon M,Roubertoux PL

更新日期：2003-09-01 00:00:00

abstract：:In a sample of 1,940 Dutch 7-year-old twin pairs we studied the etiology of individual differences in Internalizing and Externalizing behavioral problems. For the majority of twins in the sample, both maternal and paternal ratings of behavioral problems were obtained from the Child Behavior Checklist. This made it pos...

journal_title：Behavior genetics

authors： van der Valk JC,van den Oord EJ,Verhulst FC,Boomsma DI

更新日期：2003-07-01 00:00:00

abstract：:Interpretation of studies using single gene mutants is complicated by possible epistatic interactions with genetic background. Dopamine D2 receptor (Drd2) knockout mice on a C57BL/6 (B6) background show decreased basal locomotion, ethanol preference and ethanol-induced ataxia. Epistatic interactions were studied by ex...

journal_title：Behavior genetics

authors： Palmer AA,Low MJ,Grandy DK,Phillips TJ

更新日期：2003-05-01 00:00:00

abstract：:In this study we examined cross-sectional age differences in means, phenotypic covariance structure, and the underlying genetic and environmental structure of four personality constructs from Cloninger's personality system: Novelty Seeking (NS), Harm Avoidance (HA), Reward Dependence (RD), and Persistence (PS). Study ...

journal_title：Behavior genetics

authors： Heiman N,Stallings MC,Hofer SM,Hewitt JK

更新日期：2003-03-01 00:00:00

abstract：:To study the relationship between genetics and epilepsy, Wistar rats susceptible to audiogenic seizure were selected from the main breeding stock of the Ribeirão Preto School of Medicine at the University of São Paulo, Brazil, and inbred. The criteria for selection were the highest seizure severity index (SI) and shor...

journal_title：Behavior genetics

authors： Doretto MC,Fonseca CG,Lôbo RB,Terra VC,Oliveira JA,Garcia-Cairasco N

更新日期：2003-01-01 00:00:00

abstract：:Behaviors with high energetic costs may decrease in frequency in domestic animals as a response to selection for increased production. The aim of this study was to quantify production traits, foraging behavior, and social motivation in F2 progeny from a White Leghorn x red junglefowl intercross (n = 751-1046) and to p...

journal_title：Behavior genetics

authors： Schütz K,Kerje S,Carlborg O,Jacobsson L,Andersson L,Jensen P

更新日期：2002-11-01 00:00:00

abstract：:Results obtained from previous studies of word recognition, reading component skills, and reading composite measures suggest that genetic factors may be more important as a cause for reading disability among children with higher IQ scores than among those with lower IQ scores. To investigate the genetic etiology of re...

journal_title：Behavior genetics

authors： Knopik VS,Smith SD,Cardon L,Pennington B,Gayan J,Olson RK,DeFries JC

更新日期：2002-05-01 00:00:00

abstract：:The present study explored the effects of infantile stimulation (i.e., neonatal handling or NH) on the performance of 18-month-old Roman high-avoidance (RHA/Verh) and low-avoidance (RLA/Verh) rats in a swimming pool matching-to-place (SPMP) test. This test (also called repeated acquisition and place learning-set parad...

journal_title：Behavior genetics

authors： Aguilar R,Escorihuela RM,Gil L,Tobeña A,Fernández-Teruel A

更新日期：2002-03-01 00:00:00

abstract：:Extreme sampling of sibling pairs has been shown to be efficient in terms of statistical power and sample sizes (in number of sibling pairs needed to genotype) to detect a quantitative trait locus (QTL) when the residual distribution is normal. In the present study, the efficiency of extreme sampling strategies to det...

journal_title：Behavior genetics

authors： Heo M,Faith MS,Allison DB

更新日期：2002-01-01 00:00:00

abstract：:It has been hypothesized that numerous genes contribute to individual variation in human cognition. An extensive search of the scientific literature was undertaken to identify candidate genes which might contribute to this complex trait. A list of over 150 candidate genes that may influence some aspect of cognition wa...

journal_title：Behavior genetics

authors： Morley KI,Montgomery GW

更新日期：2001-11-01 00:00:00

abstract：:During middle childhood, continuous changes occur in electroencephalogram (EEG) coherence, an index of cortico-cortical connectivity of the brain. In the gradual development of EEG coher ence, occasional "growth spurts" are observed which coincide with periods of discontinuous development in cognition. Discontinuous d...

journal_title：Behavior genetics

authors： van Baal GC,Boomsma DI,de Geus EJ

更新日期：2001-11-01 00:00:00

abstract：:Alterations of peripheral magnesium (Mg) concentration have been reported in association with several behavioral disorders and sleep organization. Blood Mg regulation is under a strong genetic control, whereas brain Mg regulation does not seem to be affected. We have studied peripheral and central levels of Mg and ana...

journal_title：Behavior genetics

authors： Chollet D,Franken P,Raffin Y,Henrotte JG,Widmer J,Malafosse A,Tafti M

更新日期：2001-09-01 00:00:00

abstract：:Data from two twin studies were used to address two related questions. First, is there any association between handedness and specific speech and language impairment (SSLI) in children? Second, is there genetic influence on individual differences in handedness and, if so, are the same genes implicated in the cause of ...

journal_title：Behavior genetics

authors： Bishop DV

更新日期：2001-07-01 00:00:00

abstract：:A study was conducted to identify quantitative trait loci (QTLs) that affect learning in honeybees. Two F1 supersister queens were produced from a cross between two established lines that had been selected for differences in the speed at which they reverse a learned discrimination between odors. Different families of ...

journal_title：Behavior genetics

authors： Chandra SB,Hunt GJ,Cobey S,Smith BH

更新日期：2001-05-01 00:00:00

abstract：:Genomewide scan, as shown by recently published linkage studies on the behavior of mice or in psychiatry, provides evidence for replicated quantitative trait loci (QTL). Several studies of Alzheimer's disease have demonstrated the promise of moving from clinical diagnoses to biological signs for psychiatric investigat...

journal_title：Behavior genetics

authors： Roubertoux PL,Le Roy-Duflos I

更新日期：2001-01-01 00:00:00

abstract：:A complimentary two-phase strategy was used to detect and map quantitative trait loci (QTLs) associated with the basal locomotor response to a saline challenge (10 ml/kg). In phase 1, putative QTLs, significant at p < 0.01 or better, were identified by analysis of the strain means for 25 strains of the B x D recombina...

journal_title：Behavior genetics

authors： Koyner J,Demarest K,McCaughran J Jr,Cipp L,Hitzemann R

更新日期：2000-05-01 00:00:00

abstract：:The behaviors of male mice of the C57BL/6J (C57), CBA/Lac (CBA) and BALB/c (BALB) strains have been studied in the plus-maze and open field tests for estimation of state anxiety in the stressful novel conditions, and in the cubic box test (exploration of novel cubic box) and the partition test (behavioral reactivity t...

journal_title：Behavior genetics

authors： Avgustinovich DF,Lipina TV,Bondar NP,Alekseyenko OV,Kudryavtseva NN

更新日期：2000-03-01 00:00:00

abstract：:A new assay was designed, named checker, that measures the individual response to light in the fruitfly Drosophila melanogaster larva. In this assay the Drosophila larva apparently modulates its pattern of locomotion when faced with a choice between a dark and lit environment by orienting its movement towards the dark...

journal_title：Behavior genetics

authors： Hassan J,Busto M,Iyengar B,Campos AR

更新日期：2000-01-01 00:00:00

abstract：:Genetic and environmental determinants of self-reported alcohol consumption were investigated in a sample of 2513 twin pairs who were first assessed at age 16 and were followed-up at age 17. At age 16, 77% of the sample was drinking, and 65% of drinkers reported drinking to intoxication. Both drinking and drinking to ...

journal_title：Behavior genetics

authors： Viken RJ,Kaprio J,Koskenvuo M,Rose RJ

更新日期：1999-11-01 00:00:00

abstract：:Recent studies have identified genes that influence the length of the circadian period maintained by mice housed under constant lighting conditions. However, a less studied circadian activity variable is the amplitude of daily oscillations in locomotor activity. This parameter reflects spontaneous activity exhibited u...

journal_title：Behavior genetics

authors： Toth LA,Williams RW

更新日期：1999-09-01 00:00:00

abstract：:Human obesity is associated with greater-than-average energy intake, although relatively few studies have tested the heritability of food intake. The present study examined the genetic architecture of measured caloric intake during laboratory test meals in 36 monozygotic and 18 dizygotic twin pairs. A series of analys...

journal_title：Behavior genetics

authors： Faith MS,Rha SS,Neale MC,Allison DB

更新日期：1999-05-01 00:00:00

abstract：:We developed a zygosity questionnaire for use in young twins and assessed its validity using the results of DNA diagnosis. The participants were divided into two groups: 105 pairs of adolescent twins (12-16 years old), 47 pairs of child twins (2-12 years old), and their respective parents. The DNA diagnosis of zygosit...

journal_title：Behavior genetics

authors： Chen WJ,Chang HW,Wu MZ,Lin CC,Chang C,Chiu YN,Soong WT

更新日期：1999-03-01 00:00:00

abstract：:In an investigation into the effects of developmental isolation from all conspecifics, the Drosophila willistoni group of six sibling species responded to differing degrees: all six are reproductively isolated from D. paulistorum, the tester species. Drosophila pavlovskiana, a narrow endemic, proved the most vulnerabl...

journal_title：Behavior genetics

authors： Kim YK,Ehrman L

更新日期：1999-01-01 00:00:00

abstract：:Mutations on the period locus of Drosophila melanogaster influence circadian periods as well as the rhythm in inter-pulse intervals in male courtship song; perL mutations produce long circadian periods and courtship song rhythms and per(s) mutations produce short circadian periods and courtship song rhythms. Thus, the...

journal_title：Behavior genetics

authors： Roche JP,Talyn BC,Dowse HB

更新日期：1998-09-01 00:00:00

abstract：:Univariate and multivariate analyses of the genetic and environmental contributions to variance in adipose tissue and adipose tissue distribution were carried out in early adolescents. Stature, weight, body mass index (BMI), and five subcutaneous skinfolds were measured at half-yearly intervals in 105 MZ and DZ twin p...

journal_title：Behavior genetics

authors： Beunen G,Maes HH,Vlietinck R,Malina RM,Thomis M,Feys E,Loos R,Derom C

更新日期：1998-07-01 00:00:00

abstract：:The role of the period of the environmental cycle during gestation and infancy on the circadian period of adult hamsters was studied. Tau-mutant hamsters of all three genotypes (+/+, 24-h circadian period; +/tau, 22-h period; tau/tau, 20-h period) were conceived and raised under either a 20-h light-dark cycle or a 24-...

journal_title：Behavior genetics

authors： Refinetti R

更新日期：1998-03-01 00:00:00

abstract：:Roman high- and low-avoidance (RHA/Verh and RLA/Verh) rats are selected and bred for extreme divergence in two-way active avoidance acquisition. In addition, compared to RLA/Verh rats, RHA/Verh rats are (behaviorally and physiologically) less anxious or reactive to stressors, show increased novelty (sensation)-seeking...

journal_title：Behavior genetics

authors： Fernández-Teruel A,Escorihuela RM,Castellano B,González B,Tobeña A

更新日期：1997-11-01 00:00:00

abstract：:It is well established that many continuously distributed traits have a heritable component. However, it is often difficult to communicate to the general public the meaning of quantitative estimates of heritability. To address this problem, the present paper introduces a heuristic for communicating heritability to non...

journal_title：Behavior genetics

authors： Allison DB,Faith MS

更新日期：1997-09-01 00:00:00

abstract：:We review the literature on the familial resemblance of body mass index (BMI) and other adiposity measures and find strikingly convergent results for a variety of relationships. Results from twin studies suggest that genetic factors explain 50 to 90% of the variance in BMI. Family studies generally report estimates of...

journal_title：Behavior genetics

authors： Maes HH,Neale MC,Eaves LJ

更新日期：1997-07-01 00:00:00

abstract：:The paradise fish, a small insectivore, coinhabits marshes of Southeast Asia with several predator fish species. Its ability to recognize and avoid harmful fish may depend upon both genetic factors and experience. Here we demonstrate genetic variability between the 20-day-old larvae of two inbred strains of paradise f...

journal_title：Behavior genetics

authors： Miklósi A,Csányi V,Gerlai R

更新日期：1997-05-01 00:00:00

abstract：:Age-related changes are analyzed in the correlation of 3416 monozygotic and 3780 dizygotic U.S. twin pairs aged between 9 and 75+ years for conservatism scores derived from a 28-item social attitude inventory. The effects of the shared environment are overwhelming in twins aged 20 years or younger. In older twins, gen...

journal_title：Behavior genetics

authors： Eaves L,Martin N,Heath A,Schieken R,Meyer J,Silberg J,Neale M,Corey L

更新日期：1997-03-01 00:00:00

abstract：:Genetic and environmental influences in the determination of individual differences in self-reported symptoms of separation anxiety (SAD), overanxious disorder (OAD), and manifest anxiety (MANX) were evaluated in children and adolescents for three age groups (8-10, 11-13, and 14-16). Symptom counts for SAD and OAD wer...

journal_title：Behavior genetics

authors： Topolski TD,Hewitt JK,Eaves LJ,Silberg JL,Meyer JM,Rutter M,Pickles A,Simonoff E

更新日期：1997-01-01 00:00:00

abstract：:The effect of the maternal environment on intermale aggression was studied by means of embryo transfer of genetically selected aggressive (SAL) and nonaggressive wild house mice (LAL), and their reciprocal F1's, to standard (NMR1) females. No effect was found on the attack latency scores (ALS), i.e., aggression: all g...

journal_title：Behavior genetics

authors： Sluyter F,van der Vlugt JJ,van Oortmerssen GA,Koolhaas JM,van der Hoeven F,de Boer P

更新日期：1996-09-01 00:00:00

abstract：:In the course of the East Flanders Prospective Twin Survey (EFPTS), handedness was assessed as part of a genealogical study (Meulemans et al., 1995) in 1616 twins (808 twin pairs) aged 6 to 28. Our findings are that, in this large population-based study with known placentation and zygosity, the often observed higher f...

journal_title：Behavior genetics

authors： Derom C,Thiery E,Vlietinck R,Loos R,Derom R

更新日期：1996-07-01 00:00:00